What is it?
Cardiac output (CO) is the volume of blood pumped by one ventricle of the heart per minute.
It depends on:
- Heart Rate (HR): Number of heartbeats per minute.
- Stroke Volume (SV): Amount of blood ejected by one ventricle with each heartbeat.
How does it work?
Formula:
CO = HR × SV
Example:
- Heart rate = 70 beats/min.
- Stroke volume = 70 mL/beat.
- Cardiac output = 70 × 70 = 4,900 mL/min = 4.9 L/min.
A typical resting adult cardiac output is approximately 4–8 L/min, although it varies with body size, activity, and health.
Factors Affecting Cardiac Output
Heart Rate:
- Increasing HR can increase CO.
- Extremely high HR may reduce ventricular filling and lower stroke volume.
Stroke Volume: - Preload: Ventricular filling and stretch before contraction.
- Contractility: Strength of heart muscle contraction.
- Afterload: Resistance the ventricle must overcome to eject blood.
Relationship to Blood Pressure
- Higher CO generally increases arterial pressure when other factors remain constant.
- Lower CO may contribute to hypotension.
- Blood pressure also depends on Systemic Vascular Resistance.
Why does it matter clinically?
Cardiac output helps determine whether enough blood reaches the body’s tissues.
Reduced cardiac output may contribute to:
- Dizziness or weakness.
- Reduced organ perfusion.
- Cool extremities.
- Low blood pressure.
- Altered mental status.
These findings have multiple possible causes and do not independently establish low cardiac output.
Related
- Cardiovascular System
- Blood Pressure
- Systemic Vascular Resistance
- Dehydration
- Blood Loss
- Hypotension
- Vital Signs
Sources
- Anatomy and physiology — cardiovascular circulation
Flashcards
What is the cardiac output formula?01-foundations / anatomy-physiology / cardiovascular
Answer
Heart rate × stroke volume.
What is stroke volume?01-foundations / anatomy-physiology / cardiovascular
Answer
Blood ejected by one ventricle per beat.
Why can an extremely high heart rate reduce cardiac output?02-mechanisms / anatomy-physiology / cardiovascular
Answer
Too little ventricular filling can lower stroke volume.