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What is it?

Clostridioides difficile (C. diff) is a spore-forming bacterium that can cause inflammation of the colon and diarrhea.

  • Often associated with antibiotic use.
  • Spreads through the fecal-oral route.
  • Spores can survive on surfaces for prolonged periods.

Why does it matter?

  • May cause severe diarrhea and dehydration.
  • Can lead to serious colitis and complications.
  • Spores are difficult to eliminate with routine cleaning.
  • Healthcare facilities are important transmission settings.

What should I look for?

  • New frequent watery or loose stools.
  • Abdominal pain, cramping, or tenderness.
  • Fever or signs of dehydration.
  • Changes in bowel patterns following antibiotic use.

What should I do?

  • Follow required Contact Precautions.
  • Use gloves and gown as directed.
  • Perform hand hygiene according to facility policy.
  • During C. difficile outbreaks, use soap and water after patient care and glove removal.
  • Use approved sporicidal disinfectants according to facility procedures.
  • Report new or worsening diarrhea promptly.

Sources

Flashcards

What common symptoms may suggest C. difficile infection?01-foundations / diseases-conditions
Answer

New watery diarrhea and abdominal discomfort.

What prevention measures matter for C. difficile?03-application / diseases-conditions
Answer

Appropriate contact precautions and facility hand-hygiene protocols.